General Rules of Good Design and Layout:

When typing, use one space after punctuation.

Use fewer fonts - just because you have 500 fonts, doesn't mean you have to use them all on one page.

Limit use of centered text - large text areas should be aligned left for readability.

Balance line length - get rid of widows, those lone words hanging out on a line all by themselves.

Don't type in all caps - Caps are GREAT for calling out singular items. Overuse is overload, making it look like you are screaming at me.

Typographical punctuation - curly quotes are pretty.

Use frames and borders wisely - not everything needs a box around it.

Less clip art - photos are more inviting.

More white space - gives the eye and mind a place to rest.

Think elegant and sophisticated. Remember, less is more.